Single-Use Bioreactors: An Established Addition to Biotechnology Production
Single-Use Bioreactors: An Established Addition to Biotechnology Production
Single-use Bioreactors Market by Product (Single-use Bioreactor, Media Bags, Filtration Assembly, Others), Usage (Lab-scale, Pilot Scale, Large-scale), Type (Stirred tank, Wave-Induced, Bubble-Column, Others), Cell Type (Mammalian, bacterial, Yeast, Others), Application (Bioproduction, Research, Process Development), End user (Pharma and Biotech, CROs, Research and Academia) - Global Forecast to 2025

Single-Use Bioreactors: An Established Addition to Biotechnology Production

Meticulous Research® – leading global market research company is researching on Single-use Bioreactors Market titled- Single-use Bioreactors Market by Product (Single-use Bioreactor, Media Bags), Usage (Lab-scale, Large-scale), Type (Stirred tank, Bubble-Column), cell type (Mammalian, bacteria), application (Bioproduction, Research), End user (Pharma & biotech, CROs)- Global Forecast to 2025". According to this latest publication from Meticulous Research®, the global single-use bioreactor market will increase at a CAGR of 21.6% from 2019 to 2025 to reach $3.37 billion by 2025.

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Increase in Government Support for Biopharmaceutical Research Offers New Growth Avenues for Single-use Bioreactors Market

Governments in developed as well as developing nations are offering funding for propagation of biotechnology and biopharmaceutical research. For instance, in India, in 2017, Department of Biotechnology (DBT) and World Bank initiated a program - Innovate in India (I3) - to facilitate research related to the discovery of biopharmaceuticals. Similarly, in the U.S., National Institute of Health (NIH) collaborated with 11 biopharmaceutical companies to launch the “Partnership for Accelerating Cancer Therapies (PACT)”, a five-year public-private research collaboration. The aim of the collaboration is to develop immunotherapy for cancers with total investment of $215 million. Furthermore, in Korea, the government announced second Basic Development Plan for Bioengineering (2012). According to which, the Korean government increased biotech investments to KRW 9.7 trillion ($8.35 billion) through 2016. In addition, Korean government announced the “Government-Wide Mid- to Long-Term Action Plans to Promote R&D for National Healthcare” in 2013 - to promote growth of biotechnology and healthcare industry.

Single-Use Bioreactor Systems Segment Dominated the Single-Use Bioreactors Market in 2018

Single-use bioreactor system commanded the largest share of the single-use bioreactors market in 2018 due to its better flexibility, no sterilization demand, and low operational cost without compromising the quality of the drug produced. This addresses the complexities associated with multi‑drug manufacturing processes while providing maximum savings on the time spent to prepare the bioreactor for the next batch.

Mammalian Cells to Witness the Largest Demand Through 2025

Mammalian cells commanded the largest share of single-use bioreactor market in 2018. This is mainly attributed to proper protein folding, post-translational modifications, and product assembly, which plays an important role to initiate complete biological activity in humans.

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Asia-Pacific: The Fastest Growing Regional Market

North America commanded the largest share of the global single-use bioreactors market in 2018, followed by Europe, Asia-Pacific, Latin America, and Middle East & Africa. However, Asia-Pacific is the fastest growing regional market due to accelerated economic growth of many countries in this region and growing government focus on pharmaceutical research. In addition, government initiatives to escalate the drug development process, rising public & private funding for R&D, and rising contract research and manufacturing activities - are the key factors propelling the growth of the Asia-Pacific single-use bioreactors market.

Key players in the Single-use Bioreactors Market

In the single-use bioreactors market, the leading players are consistently developing new products with improved performance, higher efficiency, and low operational costs. In March 2018, Sartorius Stedim Biotech launched ambr 250 high throughput (ht) perfusion system for rapid cell culture perfusion process development for production of therapeutic antibodies. Similarly, in April 2016, Merck Millipore launched Mobius 1000-liter single-use bioreactor, which has greater flexibility and continuity for scale-up. Furthermore, in November 2016, Finesse Solutions, Inc. (U.S.), launched SmartVessel, a single-use 3-liter bioreactor vessel.

The key players operating in the global single-use bioreactors market are GE Healthcare, Merck Group, Danaher Corporation, Sartorius AG, Thermo Fisher Scientific Inc., Eppendorf AG, Applikon Biotechnology B.V., Solaris Biotechnology SRL, Cellexus Ltd, CESCO Bioengineering Co., Ltd., PBS Biotech, Inc., Pierre Guerin Technologies, Distek, Inc., Parker-Hannifin Corporation, Celltainer Biotech B.V., and Infors AG.

Future Outlook

Growing adoption of single-use technology since the past decade has been gaining traction at a fast pace and it is expected that most of the biopharmaceutical manufacturers will be having 100% fully disposables facility in operation in the coming years. In these facilities, the major device will be disposable bioreactors, with highest number of installations. Also, these bioreactors will be embedded with improved sensors and higher operational flexibility for multi-drug production within less time. Further, high capacity disposable bioreactors are expected to replace conventional bioreactors in large-scale manufacturing facilities.

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Single-use Bioreactors Market Segmentation:

Single-use Bioreactors Products

  • Single-use Bioreactor systems
    • Up to 10L
    • 11-100L
    • 101-500L
    • 501-1500L
    • Above 1500L
  • Media bags
  • Filtration Assemblies
  • Others

Single-use Bioreactors Molecules

  • Vaccines
  • Monoclonal Antibodies
  • Stem Cells
  • Recombinant Proteins
  • Drugs
  • Others

Single-use Bioreactors Types

  • Stirred-Tank
  • Wave-Induced
  • Bubble-Column
  • Others

Single-use Bioreactors for Cell Types

  • Mammalian cells
  • Bacterial cells
  • Yeast cells
  • Others

Single-use Bioreactors Applications

  • Bioproduction
  • Research and development
  • Process development

Single-use Bioreactors Usages

  • Lab-scale Production
  • Pilot-scale Production
  • Large-scale Production

Single-use Bioreactors End users

  • Pharmaceutical & Biotechnology companies
  • Contract Research Organizations (CROs)
  • Research and Academia

Single-use Bioreactors Segmentation by Geography

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
    • Rest of Europe
  • Asia-Pacific
    • Japan
    • China
    • India
    • Rest of Asia-Pacific
  • Rest of the World
    • Latin America
    • Middle East & Africa

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