Hemoglobinopathy is a set of hereditary blood illnesses characterised by an anomaly in haemoglobin structure. Sickle cell disease (SCD) and thalassemia are two of these diseases. Severe discomfort, shortness of breath, an enlarged spleen, and growth issues in youngsters are all common symptoms. HbS, HbE, and HbC are three other hemoglobinopathies connected to structural haemoglobin variations. Hemoglobinopathy include a wide variety of clinical symptoms, from mild hypochromic anaemia to moderate haematological illness to severe, lifelong, transfusion-dependent anaemia with multiorgan involvement.
A Hemoglobinopathy Is A Disorder Of The Red Blood Cells.It's a hereditary condition that causes the haemoglobin molecule's globin chains to have an irregular structure. The most common hemoglobinopathies diseases include sickle cell anaemia, thalassemia, haemoglobin C disease, and haemoglobin S-C disease. These are detected by a standard red blood cell (RBC) count, genetic testing, and high performance liquid chromatography, haemoglobin isoelectric focusing (Hb IEF), haemoglobin electrophoresis (Hb ELP), and a haemoglobin solubility test.
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