Digital PCR and Real-time PCR(qPCR) Market: Regional Analysis
North America is expected to holddominant position in the DigitalPCR and Real-Time PCR Market, owing to increasing number of cancer cases,favoring the demand for PCR diagnostic tools and assays. According to aNational Cancer Institute, 2016, an estimated 1,735,350 million new cases ofcancer will be diagnosed in the U.S., with around 609,640 deaths from thedisease in 2018. The number of people suffering from cancer is expected to riseto 19 million by 2024.
Polymer chain reaction (PCR)creates unlimited copies of DNA from a single strand using polymerase enzymes,primers, and multiple thermal cycles. PCR diagnostics are less prone tocross-contamination, as the procedure is conducted in automated thermalcyclers. dPCR and qPCR are common diagnostic techniques used in the research,pharma, and biotech institutes, and are widely used in variety of applications.
Real-time PCR allows specific andearly disease diagnosis, allowing speedy and selective treatment for thepatient. Also, PCR techniques have replaced the conventional infectious diseasedetection methods such as immunoassays as they are more specific and havebecome an integral part of laboratory diagnosis, thereby facilitating marketgrowth.
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Digital PCR and Real-time PCR(qPCR) Market: Dynamics
Increasing adoption of qPCR inmedical diagnosis to detect RNA viruses such as HIV and hepatitis C is expectedto propel the market growth. According to the International Journal ofNanomedicine, 2017, around 36.7 million people were affected by humanimmunodeficiency virus (HIV) and around 400 million people were affected withviral hepatitis, globally. The survey also stated that with no reliabletreatment for HIV infection, early diagnosis is a critical factor in managingAIDS patients, as it is a major cause for morbidity and mortality, globally.
Moreover, launch oftechnologically advanced products is expected to enhance the market growth. Forinstance, in November 2013, GNA Biosolutions GmbH launched an ultrafast PCRplatform, Pharos V8 platform based on laser PCR. The platform uses nanomaterialto accelerate PCR reaction, by a factor of ten, thus making it suitable to be usedin time-sensitive settings.
However, high device cost andadoption of alternative assays for disease detection and analysis is expectedto hinder the market growth.
Digital PCR and Real-time PCR(qPCR) Market: Key Players
Key players operating in theglobal digital PCR and real-time PCR market include Thermo Fisher Scientific,Inc., Bio-Rad Laboratories, Inc., Abbott Laboratories, F. Hoffmann-La RocheLtd., Qiagen N.V., Takara Bio, Inc., Danaher Corporation, Merck KGaA, Becton,Dickinson and Company, and Agilent Technologies, Inc.
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Key development
In April 2019, Thermo FisherScientific Inc. introduced Applied Biosystems QuantStudio 6 and 7 Pro Real-TimePCR Systems, which includes new specifications like facial authentication,voice command and radiofrequency identification.
In January 2019, QIAGEN N.V.announced the development of range of next-generation systems for the digitalpolymerase chain reaction (digital PCR or dPCR) one of the fastest-growingmolecular testing applications, which is expected to launch in 2020.
In 2017, Bio-Rad Laboratories,Inc. introduced iQ-Check Enterobacteriaceae real-time PCR detection kit thatcan be used for 94 samples.
In 2017, Agilent TechnologiesInc. launched AriaDx Real-Time PCR System for Clinical Diagnostics in Europe toexpand its molecular diagnostic portfolio.
In 2016, Danaher Corporationacquired Cepheid Inc. to expand its qPCR-product portfolio.
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