Melting Point ?294-295°C
Bolling Point ?387.3°C at 760 mmHg
Flash Point ?188.0±20.9 °C
Refractive Index ?1.698
Solubility ?Insoluble in water.
Chemical Products 6-Bromo-2-naphthoic acid Characteristics
CAS No:5773-80-8
Formula:C11H7BrO2
Synonyms:6-Bromo-2-naphthoic;6-BROMO-2-NAPHTHOIC ACID;6-BROMO-2-NAPHTHOLIC AICD;6-BROMO-2-NAPHTHOLIC ACID;6-Bromo-2-naphthoicacid,96%;6-BROMO-2-NAPHTHOIC ACID 99%;6-BroMo-2-naphthylacetic acid;6-Bromo-2-naphtalenecarboxylicacid;6-Bromonaphthalene-2-carboxylic acid;6-BROMO-2-NAPHTHALENE CARBOXYLIC ACID
China Export:From 2018.11 to 2019.11, total export volume of 6-Bromo-2-naphthoic acid from China was 50,754,743KG while total export value was $481,956,961. The biggest proportion of exporting volume in the last 12 months was 11.87% in 2019.05.
Chemical Products 6-Bromo-2-naphthoic acid Description
Pale brown solid
Chemical Products 6-Bromo-2-naphthoic acid Basic Attributes
CAS No：5773-80-8
Molecular Formula ：C11H7BrO2
Molecular Mass ：251.079
Exact Mass ：249.962936
PSA ：37.3 A^2
LogP ：4
EINECS ：611-572-1
InChIKeys ：NPMCAVBMOTZUPD-UHFFFAOYSA-N
H-bond Acceptor ：2
H-bond Donor ：1
SP3 ：0.00
RBN ：1
Chemical Products 6-Bromo-2-naphthoic acid Characteristics
Density ：1.6±0.1 g/cm3
Melting Point ：294-295°C
Bolling Point ：387.3°C at 760 mmHg
Flash Point ：188.0±20.9 °C
Refractive Index ：1.698
Solubility ：Insoluble in water.
Chemical Products 6-Bromo-2-naphthoic acid Safety Information
HS Code ：2916399090
Risk Code ：R36/37/38
Safety Instructions ：S26-S36/37/39-S36
Dangerous Mark ：Xn: Harmful;Xi: Irritant;
P Code ：P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Hazard Statements ：H315
Chemical Products 6-Bromo-2-naphthoic acid Production Methods
General procedure: Compound 14 (4.58 g, 20 mmol) in 1:1 THF/HA suspension of methyl 6-bromo-2-naphthoate (3b) (2.7 g, 10.0 mmol) and potassium hydroxide (1.1 g, 20.0 mmol) in methanol (50 mL) was vigorously stirred at 50 °C. The reaction mixture becomes homogeneous after the consumption of the initial compound 3b. After 8 h, the solvent was evaporated under reduced pressure (ca 2/3 vol.), water (1500 mL) was added and the unreacted ester extracted with ethyl acetate. The aqueous solution was acidified with 10percent HExample 176-BROMONAPHTHALENE-2-CARBOXYLIC ACID [(R)-1-(4-METHANESULFONYLAMINO-3-METHYLPHENYL)ETHYL]AMIDE 17A) 6-BROMONAPHTHALENE-2-CARBOXYLIC ACID To a stirred solution of 6-bromonaphthalene-2-carboxylic acid methyl ester (2 g, 8 mmol) in tetrahydrofuran (66 mL) and ethanol (22 mL) was added a solution of lithium hydroxide (542 mg, 22 mmol) in water (22 mL). The reaction was stirred at 50° C. for 16 hours. After cooling, the organic solvents were removed by evaporation, and the aqueous residue was diluted with water (100 mL) then washed with EtOAc (2.x.50 mL). The aqueous layer was acidified using 1N HCl and the products were extracted with EtOAc (3.x.50 mL). The combined organics were washed with brine (100 mL), dried (MgSOPart A. Preparation of 6-bromo-2 -naphthoic acid.; [00746] A solution of methyl 6-bromo-2-naphthoate (7.7Og, 29.0mmol) in 2:1 THF:water (15OmL) was treated with lithium hydroxide hydrate (2.44g, 58.1mmol) followed by stirring at room temperature for 48h.
