CpG-ODNs (CpG oligodeoxynucleotides) are single-stranded synthetic DNA molecules with CpG motifs. They cause TLR9-positive cells to produce pro-inflammatory cytokines and Th1 helper T-cells, which activate innate immune responses.
To improve the success of gene therapy, it is critical to employ high-quality CpG Oligodeoxynucleotide. This DNA molecule has been found in numerous investigations to boost the radioresponse of cancers that are nonimmunogenic. Additionally, it can improve the immune system's ability to combat viral infections. These advantages, however, have yet to be verified.
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