Oligonucleotides are small DNA or RNA molecules with a specified sequence of nucleotide residues that together form a complete molecule. To build a duplex chain, oligonucleotides readily bind to their respective DNA-RNA oligonucleotides in a specified sequencing fashion. Oligonucleotides are chemically manufactured molecular chains that contain phosphoramidite components of natural or chemically modified nucleosides. They have a wide range of applications in general testing, research, and forensics.
Natural oligonucleotides are made up of ribose or deoxyribose sugar phosphate as a base, which is swiftly destroyed by the nucleus in the body. Furthermore, in general testing, oligo-degradation can have an effect on cell growth and proliferation. Furthermore, the low quality of microarray-generated oligonucleotide sequences is a significant barrier to using microarray technology for Oligonucleotidase Synthesis .
TMA is an extremely simple method. It is usually used for genetic engineering. In this method, DNA is directly copied onto a microchip or other form of DNA media and then introduced into living cells. With this method TMA is said to be more potent than OVA. However, this method can be used for all forms of DNA synthesis.
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