Adults who are infected, especially those who have no symptoms, should be offered therapy because antiparasitic medication can help slow or stop the progression of disease. In other situations, it is important to balance the potential advantages of medicine in avoiding or delaying the onset of Chagas disease with the time commitment required for Chagas Disease Treatment (up to 2 months) and any potential side effects (which can occur in up to 40% of treated adult patients). Pregnant women and those who have liver or kidney disease shouldn't use benzidazole or nifurtimox. Additionally, those who have a history of neurological or psychiatric issues should not take nifurtimox. Additionally, specialised care may be needed for cardiac, digestive, or neurological symptoms.
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