If the target angiographic endpoint is not obtained after 6 to 8 mL (three to four syringes) of 500- to 700-m particles have been injected into the uterine artery, the standard protocol for UAE with ES is to start with 500- to 700-m particles and upsize to 700- to 900-m particles.
The ideal size of an Embolization Particle is determined by the type of tissue it is aiming at. When targeting a tumour, it must be surrounded by blood arteries that supply it with nutrients. Based on the type of vascular feeding the tumour, the particle size should be tailored. This is a difficult undertaking that has necessitated the development of different techniques. One study found that following vascular embolization, six to twelve times the amount of microspheres were discovered within a simulated HCC tumour. To avoid overhanging skin in the case of extracranial tumours, the particles should be restricted to the tumour bed. Larger particles may cause necrosis in the surrounding tissue, which is only useful if the tumour is located in the centre of the mass.
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