Canarypox (ALVAC), modified vaccinia Ankara (MVA), and adenovirus vaccines are examples of live recombinant vaccines based on viral vectors. These can be used alone or in a prime–boost paradigm with other vaccinations to generate cellular and humoral responses.
Recombinant vaccines have a number of advantages. They are simple to make and can be put into a variety of carriers. In addition, there is room for greater genetic engineering. In addition, when compared to other types of immunizations, they pose fewer dangers.
The low immunogenicity of recombinant subunit vaccines, as well as that of conventional subunit vaccines, necessitates repeated immunisation and the use of adjuvants.
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