NucleicAcid Isolation and Purification Market, by Product Type (DNA & RNAExtraction and Purification Kits, Reagents, and Instruments), by Method(Column-based Isolation and Purification, Reagent-based Isolation andPurification, Magnetic Bead-based Isolation Purification, and Others), by Type(DNA Isolation and Purification and RNA Isolation and Purification), byApplication (Diagnostics, Precision Medicine, Drug Discovery and Development,and Others), by End User (Pharmaceutical and Biotech Companies, Hospitals and DiagnosticsLaboratories, Research Centers, and Contract Research Organizations ), and byRegion (North America, Europe, Asia Pacific, Latin America, Middle East, andAfrica) - Size, Share, Outlook, and Opportunity Analysis, 2018 – 2026
High quality DNA and RNA areimportant for a wide variety of research and clinical applications.Purification or isolation of nucleic acids is the first step in most molecularbiological studies and in all recombinant DNA techniques. The extraction of nucleicacids from biological material requires cell lysis, inactivation of cellularnucleases, and separation of the desired nucleic acid from cellular debris.Methods for purifying nucleic acids from cell extracts are often combinationsof extraction/precipitation, chromatography, centrifugation, electrophoresis,and affinity separation. Pure nucleic acid has applications in emerging fieldssuch as genetic engineering, molecular diagnosis, forensics, and researchrelated to life sciences.
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Nucleic Acid Isolation andPurification Market Drivers
Increasing demand for nucleicacid test that is required for pipeline studies of genetic engineering andmolecular diagnostics is the key driver for nucleic acid isolation andpurification market growth. For Instance, in September 2012, GlaxoSmithKlineinitiated Phase 1 clinical study to evaluate the effects of chemotherapy andadoptive immunotherapy with T cells engineered to recognize NY-ESO-1 peptide inpatients with unresectable, metastatic or recurrent synovial sarcoma. T immunecells are genetically engineered to express tumor-specific T cell receptor(TCR) genes and thereby kill cancer cells. The study is expected to complete byMay 2020.
However, low adoption ofautomated nucleic acid isolation and purification procedures in emergingeconomies is a key factor restraining the global nucleic acid isolation andpurification market growth.
Nucleic Acid Isolation andPurification Market- Regional Analysis
On the basis of region, theglobal nucleic acid isolation and purification market is segmented into NorthAmerica, Latin America, Europe, Asia Pacific, Middle East, and Africa.
Increasing merger and acquisitionactivities in North America are expected to drive the nucleic acid isolationand purification market size. For Instance, in May 2018, Agilent TechnologiesInc. acquired Lasergen, Inc. in a US$ 105 million deal. The collaboration hasbeen done to develop next-generation sequencing workflow solutions for clinicalapplications.
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Furthermore, key players inEurope are focused on adopting acquisition strategies in order to enhance theirmarket share. This in turn is expected to boost growth of the nucleic acidisolation and purification market in the region. For Instance, in February2017, Qiagen Inc. acquired OmicSoft Corp. OmicSoft is recognized for its suiteof software solutions that enable researchers to analyze and visualize theirown datasets and compare them to massive volumes of publicly available ‘omics’datasets. This acquisition aims at adding feature to the management, analysis,and sharing of both primary data and analyzed results, while also expanding therange of Qiagen’s translational and clinical applications.
Key players operating in thenucleic acid isolation and purification market include QIAGEN Inc., ThermoFisher Scientific., F. Hoffmann-La Roche Ltd, Merck KGaA,, Agilent TechnologiesInc., Illumina, Inc., Takara Bio Inc., Promega Corporation, General ElectricCompany, Danaher Corporation, New England Biolabs, and Bio-Rad Laboratories.
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