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Chemical Products DL-Tryptophan Production Methods
CAS No:54-12-6
Formula:C11H12N2O2
Synonyms:H-DL-Trp-OH
Chemical Products DL-Tryptophan Description
DL-Tryptophan is an endogenous metabolite.
Chemical Products DL-Tryptophan Basic Attributes
CAS No:54-12-6
Molecular Formula :C11H12N2O2
Molecular Mass :204.23
Exact Mass :204.089874
PSA :79.1 A^2
LogP :-1.1
EINECS :200-194-9
InChIKeys :QIVBCDIJIAJPQS-UHFFFAOYSA-N
H-bond Acceptor :3
H-bond Donor :3
SP3 :0.18
RBN :3
Chemical Products DL-Tryptophan Characteristics
Appearance :White to light beige or light yellow Powder
Density :1.4±0.1 g/cm3
Melting Point :289-290 °C (dec.)(lit.)
Bolling Point :447.9±35.0 °C at 760 mmHg
Flash Point :224.7±25.9 °C
Refractive Index :1.698
Solubility :H2O: 10 g/L (20 ºC);methanol: water (7:3): soluble
Storage Condition :Store at RT.
BRN :86196
Stability :Stable. Incompatible with strong oxidizing agents, strong acids.
Chemical Products DL-Tryptophan Safety Information
HS Code :29339990
UN No. :NONH for all modes of transport
WGK_Germany :1
Risk Code :22-36/37/38-37/38-41
Safety Instructions :24/25-36/37/39-36-26
RTECS No. :YN6129200
Dangerous Mark :Xi
P Code :P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
Hazard Statements :H315
Chemical Products DL-Tryptophan Product Usage
An amino acid precursor of serotonin and melatonin.
Chemical Products DL-Tryptophan Production Methods
Using indole and α-acetamidoacrylic acid as raw materials, after the reaction in glacial acetic acid-acetic anhydride medium is complete, NaOH is adjusted to basicity, extracted with ether, and then extracted 3 times with dilute sodium hydroxide, combined with sodium hydroxide solution, added A few grains of sodium bisulfite, cooled to 5 ℃, adjusted to neutral with concentrated hydrochloric acid, precipitated acetyl-DL-tryptophan, refluxed in 10% sodium hydroxide solution, concentrated and crystallized to obtain DL-tryptophan.
Chemical Products DL-Tryptophan Material and Products
Material :
2-Methoxyethanol, DL-Serine, 2-Acetamidoacrylicacid, Aceticanhydride, INDOPHENOLBLUE, N-[(tert-Butoxy)carbonyl]-D-tryptophan, SULFUROUSACID, Acrolein, INDOPHENOL, L-Tyrosine, Sodium sulfate, Formaldehyde, Phenylhydrazinehydrochloride, methyltryptophan, 2-Methylindole, Dimethylamine, 3-chloroalanine, L-Tryptophan, Starch, N-Acetyl-L-tryptophan
Products :
5-(1H-INDOL-3-YLMETHYL)-3-METHYL-2-THIOXO-4-IMIDAZOLIDINONE, 3-(3-Indolyl)-2-oxopropanoicacid, 3-Methyl-1H-indole, 2-(1H-indol-3-yl)acetaldehyde, PHENYLTHIOHYDANTOIN-TRYPTOPHAN, 2-Aminoacetophenone, D-Tryptophan, HARMANE-1,2,3,4-TETRAHYDRO-3-CARBOXYLICACID, Indole, Indole-3-carboxaldehyde