These genetic flaws can cause primary immunodeficiency diseases like combined immunodeficiency disease, DiGeorge syndrome, hypogammaglobulinemia, Bruton's disease, and others. Secondary immunodeficiency disease is caused by a variety of factors, including malnutrition, diabetes, radiation, severe burns, and others. Secondary immunodeficiency diseases include HIV/AIDS, leukemia, viral hepatitis, multiple myeloma, and other illnesses. Antibiotics, immunoglobulin therapy, antiviral drugs, stem cell therapy, and gene therapy are all options for treating immune-deficiency diseases.
Immunodeficiency disorders or diseases compromise a person's immune system's ability to fight microbial infection, leaving them immunocompromised. As a result, people who have immunodeficiency diseases or disorders are more likely to get sick. Congenital and acquired immune deficiency disorders are both possible. A congenital immunodeficiency disorder appears at birth, whereas an acquired immunodeficiency disorder appears later in life. For example, primary immunodeficiency disease is a congenital immunodeficiency disease caused by a mutation in genes that control the immune system.
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