Streptozocin is used to treat pancreatic islet cell carcinoma that has spread to the liver. In both bacterial and mammalian cells, streptozocin inhibits DNA synthesis. Specific interaction with cytosine moieties causes DNA degradation in bacterial cells.
Streptozocin is a drug approved by the United States Food and Drug Administration (USFDA) to treat pancreatic islet cell cancer. Streptozocin is classified as an alkylating agent, which causes a chemical reaction that damages the DNA in a cell to produce anti-cancer effects. Streptozocin-induced DNA damage results in cell death. Streptozocin causes hyperglycemia by damaging pancreatic cells; therefore, it is used in medical research to create an animal model for hyperglycemia.
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