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Investments in the Gamma Knife Market machine must be substantial. As a result, there are just a few medical facilities where patients can receive gamma knife treatment. Additionally, some patients are burdened by the exorbitant cost of their treatment. For some circumstances, it might also be necessary to provide radiation treatments more than once. The price of the treatment will rise as a result. The severity of the tumour, the facility, and the country of treatment all affect how much the treatment will cost. Players in the Gamma Knife industry primarily use a variety of research initiatives and strategic alliances as their main business models. Elekta AB, Huiheng Medical, Varian Medical Systems, Accuray Incorporated, GE Healthcare, Philips Healthcare, Brainlab, American Radiosurgery Inc., Hitachi America, and Nordion Inc. round out the top ten manufacturers of gamma knives.