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Four essential parts make up prefilled syringes: a plunger, stopper, barrel, and needle. The plunger and stopper need to fit snugly inside the barrel for the mechanism to work properly, but they should glide through it when pressure is applied. Elastomer stoppers' slightly tacky surface, which tends to rub against the surface of the barrel, can occasionally cause issues.
Delivering the API in a single, fluid push after the break-loose force has been neutralised is also essential for positive patient experiences. The glide force, which is what this is called, should be as constant as possible. In particular, consistent glide forces are necessary for syringe drivers, which are tiny, battery-operated devices used to subcutaneously deliver medications to palliative care patients at a constant rate.
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https://knackersblogger.blogspot.com/2022/11/prefilled-syringes-have-four-key.html
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