Poliomyelitis could be a highly contagious poliomyelitis disease caused by the poliovirus. it is also referred to as acute anterior poliomyelitis or polio. The virus could be a single-stranded RNA virus that belongs to the Enterovirus genus. Poliovirus has three serotypes: P1, P2, and P3, and developing antibody to 1 serotype doesn't end in considerable immunity to the others. The virus is spread largely through the fecal-oral route, consuming contaminated food or water, and therefore the oral-oral route, which is a smaller amount prevalent. Whether or not no symptoms are visible, people who are sick might spread the disease for up to six weeks.
Poliovirus infects cells within the central systema nervosum after colonising the duct, notably the gut and oropharynx. After a couple of week, it invades local lymphatic tissue and enters the circulation. Poliovirus replication in motor neurons of the anterior horn and brain stem induces death, leading to the classic symptoms of poliomyelitis.
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