Molecular Modeling Approaches Help Develop Targeted Drugs for COVID-19
Phytochemical inhibitors such as ursolic acid, oleanolic acid, and carvacrol are being used in integrated molecular modeling approaches to combat the novel coronavirus (COVID-19) in individuals. Since ursolic acid possesses antiviral, antimicrobial, and antioxidant properties, pharmaceutical companies are using this therapeutic agent to control the viral replication of coronavirus in patients. Ursolic acid falls under the list of FDA (Food & Drug Administration)-approved antiviral compounds that can be used in supplements and capsules to inhibit the viral replication of COVID-19 in patients. However, there is still a scarcity of reports that validate the phytochemical function of ursolic acid, which is derived from antiviral herbs. This is expected to impact the expansion of the ursolic acid market.
Pharmaceutical companies in the ursolic acid market are increasing their research in molecular modeling approaches to target drug designs that can effectively treat COVID-19.
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Stearate-free Ursolic Acid Capsules Gain High Demand Due to Novelty in Nutrition Sector
The high prevalence of cardiovascular diseases in individuals has fueled the demand for ursolic acid capsules. Since individuals are aiming to achieve lean muscles, Labrada Nutrition – a manufacturer of dietary supplements is increasing its advertisement spending to fuel the uptake of its lean muscle optimizer ursolic acid capsules. Recent peer-reviewed and published studies are boosting the credibility credentials of companies in the ursolic acid market who are increasing their production capabilities to develop ursolic acid capsules.
Companies in the ursolic acid market are exploring opportunities in packaging options such as increasing the availability of ursolic acid capsules in glass bottles. There is a growing demand for stearate-free ursolic acid capsules that support the development of lean muscles. This newly discovered substance is creating novelty in the health & nutrition sector.
Ursolic Acid Supplements Used for Muscle Mass Gain and Fat Reduction
Ursolic acid appears to be a promising body recomposition agent. This has led to the popularity of ursolic acid supplements and capsules being used by individuals to increase muscle mass and decrease fat mass. Thus, health-conscious individuals are joining the bandwagon of weight loss and increasingly opting for ursolic acid supplements. As such, the ursolic acid market is projected to reach US$ 16.8 Mn by the end of 2030.
Apart from common individuals, athletes are another promising target audience for ursolic acid supplements. The ursolic acid supplements are being highly publicized for reducing fat accumulation and increasing muscle mass gain when in a fed state. Manufacturers in the ursolic acid market are broadening their revenue streams through e-Commerce platforms to capitalize on revenue opportunities.
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Researchers Increase Scope for Experiments in Plant-derived Biologically Active Products
Ursolic acid displays efficacious therapeutic potentials. However, there is a need for more evidence to sufficiently prove the credibility of ursolic acid powder and supplement products. Researchers at South Korea’s Inha University and Inje University suggest that the exact mechanisms of ursolic acid’s health benefits are still unclear. However, ursolic acid’s health benefits for the brain, liver, heart, and muscles outweigh its lack of evidence for product development. As such, the ursolic acid market is predicted to expand at a healthy CAGR of 7.5% throughout the forecast period.
Many researchers claim that ursolic acid aids in the prevention and treatment of chronic diseases. The awareness about plant-derived biologically active products is surging in the ursolic acid market. This has helped to treat chronic diseases such as obesity, cancer, diabetes, and liver diseases.
Nano-drug Delivery Systems Eliminate Issues of Poor Water Solubility in Clinical Applications
The evolution from small molecule to nano-drug delivery systems is transforming the ursolic acid market. Nano-drug delivery systems are a novel approach toward cancer therapy. Since cancer is a devastating condition, pharmaceutical companies are increasing their R&D capabilities to harness the advantages of ursolic acid extracts. The ursolic acid is gaining much attention in the ursolic acid market, owing to its superior therapeutic actions and fewer adverse events in cancer therapy.
In addition, the high availability of ursolic acid in plants saves on production cost for pharmaceutical companies. This substance is gaining increased attention for its antimicrobial, anti-diabetic, and anti-inflammatory properties. Ursolic acid and its derivatives are being used to inhibit a series of cancer cell growth, thus validating its potential as a promising chemotherapeutic agent. Since poor water solubility and permeability of ursolic acid is greatly hindered in clinical applications, pharmaceutical companies are increasing their production capacities to construct nano-drug delivery systems.
Manufacturers Capitalize on Growing Juice Industrial Waste to Develop Bioactive Compounds
Apple waste is a byproduct of the juice industry. This raw material is cost-efficient and does not have a robust industrial utilization. Hence, companies in the ursolic acid market are capitalizing on this opportunity to accumulate large volumes of apple waste, since apple skin is a rich source of ursolic acid. Apart from apple, orange peels, rosemary, and thyme are rich in ursolic acid. In this way, pharmaceutical companies are tapping into opportunities in the juice industry to acquire readily available raw material as apple and other fruit waste.
The growing world population is another key driver for the growth of the ursolic acid market, as more food waste is generated. There is a need for the development of the agricultural business, which will help to increase the availability of bioactive compounds such as ursolic acid. Manufacturers are adopting innovative extraction techniques to take advantage of the growing industrial waste in the form of apple pomace and orange peels.
