Chemical Products Oxcarbazepine Description
Chemical Products Oxcarbazepine Description
Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.Target: Sodium ChannelOxcarbazepine is an antiepileptic drug with a chemical structure similar to carbamazepine, but with different metabolism. Oxcarbazepine is rapidly reduced to 10,11-dihydro-10-hydroxy-carbazepine (monohydroxy derivative, MHD), the clinically relevant metabolite of oxcarbazepine. MHD has (S)-(+)-
Chemical Products Oxcarbazepine Basic Attributes
CAS No：28721-07-5
Molecular Formula ：C15H12N2O2
Molecular Mass ：252.27
Exact Mass ：252.089874
PSA ：63.4 A^2
LogP ：1.7
EINECS ：249-188-8
InChIKeys ：CTRLABGOLIVAIY-UHFFFAOYSA-N
H-bond Acceptor ：2
H-bond Donor ：1
SP3 ：0.07
RBN ：0
Chemical Products Oxcarbazepine Characteristics
Appearance ：white solid
Density ：1.3±0.1 g/cm3
Melting Point ：215-216°C
Bolling Point ：457.2°C at 760 mmHg
Flash Point ：2℃
Refractive Index ：1.662
Solubility ：soluble in DMSO(~9 mg/mL), methanol, water, ethanol and acetone.
Storage Condition ：Store at RT
Vapor Pressure ：7.6X10-9 mm Hg at 25 deg C (est)
Chemical Products Oxcarbazepine Safety Information
HS Code ：2933990090
UN No. ：UN 1648 3 / PGII
WGK_Germany ：3
Risk Code ：22-36-20/21/22-11
Safety Instructions ：16-36/37
RTECS No. ：HN8445000
Dangerous Mark ：Xn,F
P Code ：P301 + P312 + P330
Hazard Statements ：H302
Chemical Products Oxcarbazepine Product Usage
The keto derivative of Carbamazepine. Used as an anticonvulsant
Chemical Products Oxcarbazepine Material and Products
Material ：
10-Methoxyiminostilbene, 10,11-DIHYDROCARBAMAZEPINE, Triphosgene, 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE, Chlorosulfonylisocyanate, Sodiumcyanate, 4-Chlorobenzaldehyde, PHOSGENE, Benzaldehyde, Acetaldehyde
