Clinical trials are very important to know more about cancer prevention & cancer treatment vaccines. Researchers are testing vaccines for different types of cancer, which include:
1. Cervical cancer: The FDA approved HPV vaccines that prevent cervical cancer. Research continues on vaccines that aid to treat each stage of cervical cancer.
2. Brain tumors: Many of the studies include children and teens that are testing treatment vaccines aimed at certain molecules on the surface of brain tumor cells. Some focus on newly found brain cancer and the rest focus on cancer that has come back or recurred.
3. Bladder cancer. Researchers are testing how well a vaccine created from a virus altered with the HER2 antigen works. These antigens or molecules stay and live on the surface of some bladder cancer tumors. The virus can assist to teach the immune system to locate and destroy these tumor cells. Researchers want to know whether standard bladder cancer treatment or standard treatment works better with a vaccine.
4. Breast cancer: Many studies are testing treatment vaccines for breast cancer, to be given alone or with other treatments. Some researchers are working to get vaccines that prevent breast cancer.
5. Leukemia: Treatment vaccines for various kinds of leukemia, such as acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) being examined. Some of them are to help other treatments, such as a bone marrow/stem cell transplant, work better. Other vaccines help the immune system destroy cancer which is made from a person’s cancer cells and other cells.
6. Kidney cancer: Many cancer vaccines to treat kidney cancer are being tested by researchers. They are also testing vaccines to prevent kidney cancer in its latest stages from coming back.
7. Colorectal cancer. Treatment vaccines are being made by researchers that tell the body to attack cells with antigens that may cause colorectal cancer. These antigens include MUC1, guanylyl cyclase C, carcinoembryonic antigen (CEA), and NY-ESO-1.
8. Lung cancer. Lung cancer treatment vaccines target antigens in clinical trials.
9. Prostate cancer. Doctors can Sipuleucel-T is a vaccine that is used to treat people with prostate cancer that has spread. Now studies are examining to notice if the vaccine can help people with prostate cancer at earlier stages.
10. Pancreatic cancer: Researchers are working on many treatment vaccines developed to promote the immune system’s response to pancreatic cancer cells. The vaccine can be given as the singular treatment or along with another treatment.
11. Myeloma. Many clinical trials are examining the vaccines for people with multiple myeloma who are near remission. This means doctors can no longer see cancer in the body with no symptoms. Researchers are also testing vaccines in people who need to have an autologous bone marrow transplant.
12. Melanoma. Researchers are testing many melanoma vaccines that can be given alone or with other treatments. Destroyed melanoma cells and antigens in the vaccines help the immune system to destroy other melanoma cells in the body.