Currently, there is no effective mitochondrial disorders treatment despite major advances in understanding of the molecular mechanisms. Mitochondrial disorders, such as mitochondrial myopathy, diabetes mellitus and deafness (DAD), leber's hereditary optic neuropathy (LHON), Leigh syndrome, etc. are inherited chronic disorders categorized by a range of genetic and biochemical mitochondrial mutations and defects. Mitochondrial disorders affect many organs, such as kidney, skeletal muscles, liver, heart, brain, and respiratory system, among others. Mitochondrial disorders treatment is typically performed with nutritional supplements, co-factors, vitamins, and off-label drugs approved for other indications.
Mitochondrial disorders can cause harm to an individual's health. Mitochondrial disorders can cause a person to be deformed and it can even lead to death if not treated in time. Moreover, there are different types of mitochondrial disorders according to the different kinds of defects they contain. Mitochondrial disorders can also cause genetic abnormalities. This happens when there is a problem with the egg cells that produce the nucleus in the embryo cell of the mother. If the defective cells are not treated then an individual will suffer from congenital heart disease and certain types of cancer in the body. There is also a chance of mental retardation and learning disabilities in children caused by such diseases.
Thus, it is very important to detect these disorders at the earliest and get the required treatment so that the child becomes healthy and grows up healthily. Mitochondrial disorders can affect both men and women and cause a wide variety of problems in their lives. Women usually face mental, economic, and social problems due to their condition. Hence, it is very important to get complete medical attention for all those who are affected by these disorders before it gets worse. It is a very common in women nowadays and almost every woman experiences this at some point of time. Thus, every woman is required to consult a medical advisor who can guide them through the process of diagnosis, treatment and recovery.
Mitochondrial disorders are long-term, genetic, often inherited disorders that occur when mitochondria fail to produce enough energy for the body to function properly. Symptoms might include muscle weakness, developmental delays, and poor growth. There are no cures, but physiotherapy and medication can manage symptoms. Mitochondrial disorders treatment may include vitamins and supplements (such as B complex vitamins, Coenzyme Q10, Alpha lipoic acid, Creatine, L-carnitine (Carnitor), and L-Arginine), Exercises (such as running, walking, cycling, dancing, swimming, and others), energy conservation, and other treatments, such as speech therapy, respiratory therapy, physical therapy, and occupational therapy.
Mitochondrial disorders treatment varies considerably; the treatment depends on the severity of the condition. At present, vitamins and supplements are the mainstay of treatment for mitochondrial disorders. Most experts use a combination of vitamins and supplements and prevent worsening of symptoms during times of illness and physiologic stress. Current recommended mitochondrial disorders treatment fall into three groups, such as physical therapies, pharmacological agents, and nutritional supplements with vitamins and cofactors. However, further research is necessary to examine the effectiveness of these interventions.
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