Pehr Edman published a protein sequencing method, Edman Degradation, in 1950. This method made it possible to determine the extended sequences of peptides or whole proteins and is widely used today. The method removes and identifies amino acid residues at...
Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins.
Among the endoproteases used for protein digestion, serine protease trypsin is the most common one, as it generates peptides that are highly amenable to MS analysis. Depending on the preceding workflow, the enzymatic digestion of proteins is performed eit...
Edman degradation sequencing is to sequentially cut out each amino acid at the N-terminal of the protein through chemical reaction and then use HPLC liquid chromatography to identify the ID of the amino acid, and the obtained amino acid sequence informati...
Creative Proteomics is an integrated CRO company committed to providing a full range of services in order to support various proteome research projects, from the identification of single proteins to large-scale proteomic studies. Recently, Creative Proteo...
The Cytokine division belongs to Creative Proteomics, which specializes in providing cytokine research and analysis services for researchers in the pharmaceutical and biotechnology industries, as well as academic institutes and government agencies. Creati...
The organism undergoes thousands of biochemical reactions every moment to maintain our growth, development and energy metabolism. Under normal circumstances, these biochemical reactions proceed smoothly step by step through various cycles or certain steps...
Fat, also known as triglyceride, is made by condensing one molecule of glycerol and three fatty acids. The source of fatty acids in the body: one is the body's own synthesis, and the other is the food supply. Some unsaturated fatty acids cannot be synthes...
Biotin is a naturally occurring metabolic enzyme cofactor that is active only when covalently linked to the enzyme by the action of a specific protein-biotin ligase. Any biotinylated substrate can bind tightly to protein affin and streptavidin.
Pronalyse is a new division of Creative Proteomics, which is an integrated CRO company with rich experience in providing drug development services. Building on its years of experience, Creative Proteomics Pronalyse announces the launch of its metabolite i...
Metabolomics, a subdivision of Creative Proteomics, is dedicated to providing metabolomics services based on cutting-edge LC-MS technology for biomedical research institutions, biotechnology companies, and pharmaceutical companies. Creative Proteomics has...
The Cytokine division belongs to Creative Proteomics, which specializes in providing cytokine research and analysis services for researchers in the pharmaceutical and biotechnology industries, as well as academic institutes and government agencies. Creati...
Mitochondria are dynamic organelles with bilayer membranes. Mitochondria have multiple functions, not only providing energy to cells through oxidative phosphorylation to produce ATP, but also involved in regulating processes such as calcium homeostasis, r...
Bile acids are the main components of bile and are synthesized in the liver from cholesterol through a series of enzymatic reactions. Bile acids can be divided into free bile acids and conjugated bile acids according to their structures.
Cytokines function in autocrine, paracrine or endocrine forms, and can regulate cell growth and differentiation, modulate immune response and participate in the development of various diseases such as inflammation by binding to the corresponding receptors...