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PNH (paroxysmal nocturnal hemoglobinuria) is a rare disease that manifests clinically as a variety of nonspecific symptoms. It primarily causes complications through intravascular hemolysis, thrombosis, and bone marrow failure. This activity reviews the evaluation and treatment of paroxysmal nocturnal hemoglobinuria and emphasises the role of the interprofessional team in evaluating and treating patients with this condition.
Paroxysmal Nocturnal Hemoglobinuria Therapeutics is a rare disease that manifests clinically with a variety of symptoms, the most common of which are hemolytic anemia, hemoglobinuria, and somatic symptoms such as fatigue and shortness of breath. PNH is also associated with thrombosis, renal insufficiency, and, in the later stages of the disease, bone marrow failure.