More than 85 small molecule protein degraders are currently being evaluated for the treatment
The concept of targeted protein degradationpresents revolutionary drug development opportunities and is anticipated tobring about a paradigm shift in modern healthcare. The first targeted protein degrader, called proteolysistargeting chimera (PROTAC), was developed about a decade ago. Presently, avariety of other such chemical entities and molecular glues are underinvestigation. In fact, certain pipeline candidates are already in the mid tolate-phase trials and are anticipated to soon enter the market.
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The USD 3.6 billion (by 2030) financial opportunitywithin the target protein degradation market has been analyzed across thefollowing segments:
§ Type of payment oflicensing agreements
§ Upfront payments
§ Milestone payments
§ Type of proteindegrader
§ Degronimids
§ PROTACs
§ SARDs / SERDs
§ Specific BET and DUBinhibitors
§ Other proteindegraders
§ Therapeutic area
§ Neurodegenerativedisorders
§ Oncological disorders
§ Other therapeuticareas
§ Route ofadministration
§ Oral
§ Intravenous
§ Other routes
§ Key geographicalregion
§ North America
§ Europe
§ Asia-Pacific
The Targeted Protein Degradation Market: Focus on Therapeuticsand Technology Platforms (based on Degronimids, ENDTACs, EpichaperomeInhibitors, Hydrophobic Tags, IMiDs, LYTACs, Molecular Glues, PHOTACs, PROTACs,Protein Homeostatic Modulators, SARDs, SERDs, SNIPERs, and Specific BET and DUBInhibitors), 2020-2030 report features thefollowing companies, which we identified to be key players in this domain:
§ Arvinas
§ Captor Therapeutics
§ Celgene
§ Genetech
§ Kymera Therapeutics
§ Mission Therapeutics
§ Progenra
§ Radius Health
§ SanofiGenzyme
§ Zenopharm
Table of Contents
1. Preface
2. Executive Summary
3. Introduction
4. Current Market Landscape
5. Company Profiles
6. Clinical Trial Analysis
7. KOL Analysis
8. Publication Analysis
9. Funding and Investment Analysis
10. Partnerships and Collaborations
11. MarketSizing and Opportunity Analysis
12. Executive Insights
13. Concluding Remarks
14. Appendix 1: Tabulated Data
15. Appendix 2: List of Companies andOrganizations
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Contact Details
Gaurav Chaudhary
+1 (415) 800 3415
gaurav.chaudhary@rootsanalysis.com
