BACKGROUND:
Honey is recognized for its therapeutic properties from ancient civilizations. Lately, the mechanism of action of Manuka honey in wound healing, epithelial regeneration, and ulcer treatment options has been revealed. Get additional information about bulk honey buyers nz
OBJECTIVE:
Within the current review, the health perspectives of honey, its chemical composition with unique reference to flavonoids, polyphenol, and other bioactive trace compounds used in tissue regeneration have already been discussed in detail.
Methods:
We undertook a structured search using wide spectrum sources like Google Scholar, PubMed, and Scopus.
Results:
The included papers showed that Manuka honey can inhibit the approach of carcinogenesis by controlling distinct molecular processes, and progression of cancer cells. Manuka honey has been identified to possess several biological activities, which includes antioxidant, antimicrobial and anti-proliferative capacities. Scientists try to use Manuka honey in the region of tissue engineering to design a template for regeneration. Naturally derived antibacterial agents of Manuka honey are numerous mixtures of different compounds, which can influence antibacterial capacity. The non-peroxide bacteriostatic properties of Manuka honey are related together with the presence of methylglyoxal (MGO).
CONCLUSION:
As well as bacterial growth inhibition, glyoxal (GO) and MGO from Manuka honey can enhance wound healing and tissue regeneration by their immunomodulatory property. Additional studies are necessary to provide detailed information about active elements of Manuka honey and their possible efficacy in different diseases.
