views
Encouragingclinical results across various metabolic, hematological and ophthalmicdisorders have inspired research groups across the world to focus their effortson the development of novel gene editing therapies. In fact, the gene therapypipeline has evolved significantly over the past few years, with three productsbeing approved in 2019 alone; namely Beperminogene perplasmid (AnGes),ZOLGENSMA® (AveXis) and ZYNTEGLO™ (bluebird bio). Further, there are multiplepipeline candidates in mid to late-stage (phase II and above) trials that areanticipated to enter the market over the next 5-10 years.
TheUSD 11.6 billion (by 2030) financial opportunity within the Gene Therapy Market has been analyzed across the followingsegments:
Keytherapeutic areas
· Autoimmune disorders
· Cardiovascular diseases
· Genetic disorders
· Hematological disorders
· Metabolic disorders
· Ophthalmic disorders
· Oncological disorders
· Others
Typeof vector
· Adeno associated virus
· Adenovirus
· Herpes simplex virus type 1
· Lentivirus
· Plasmid DNA
· Retrovirus
· Vaccinia Virus
Typeof therapy
· Ex vivo
· In vivo
Typeof gene modification
· Gene augmentation
· Immunotherapy
· Oncolytic therapy
· Others
Routeof administration
· Intraarticular
· Intracerebellar
· Intramuscular
· Intradermal
· Intravenous
· Intravitreal
· Intravesical
· Subretinal
· Others
Keygeographical regions
· North America
· Europe
· Asia-Pacific
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TheGene Therapy Market (3rd Edition), 2019-2030 report features the followingcompanies, which we identified to be key players in this domain:
· Advantagene
· Advaxis
· BioMarin
· bluebird bio
· FKD Therapies
· Freeline Therapeutics
· GenSight Biologics
· Gradalis
· Inovio Pharmaceuticals
· Marsala Biotech
· Orchard Therapeutics
· Pfizer
· Sarepta Therapeutics
· Spark Therapeutics
· Tocagen
· Transgene
· uniQure Biopharma
· VBL Therapeutics
· ViroMed
Tableof Contents
1. Preface
2. Executive Summary
3. Introduction
4. Gene Delivery Vectors
5. Regulatory Landscape and Reimbursement Scenario
6. Competitive Landscape
7. Marketed Gene Therapies
8. Key Commercialization Strategies
9. Late Stage (Phase II/III and Above) Gene Therapies
10. Emerging Technologies
11. Promising Therapeutics Areas
12. Patent Analysis
13. Mergers and Acquisitions
14. Funding and Investment Analysis
15. Cost Price Analysis
16. Big Pharma Players: Analysis of Gene Therapy RelatedInitiatives
17. Market Forecast and Opportunity Analysis
18. Vector Manufacturing
19. Case Study: Gene Therapy Supply Chain
20. Conclusion
21. Interview Transcripts
22. Appendix 1: Tabulated Data
23. Appendix 2: List of Companies and Organizations
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