VasculitisTreatment Market – Global Industry Insights, Trends, Outlook, and OpportunityAnalysis, 2018-2026
A group of disorder caused by theinflammation of blood vessels is known as vasculitis (plural: vasculitides),also called angiitis. Vasculitis includes inflammation of arteries, veins,and/or capillaries. The disease can affect both males and females equallywithout any age specifications. Quite afew forms of vasculitis are present, and their scientific characteristics canvary considerably in terms of severity, symptoms, as well as the duration ofdisease. It depends on the types of blood vessels that are affected by thedisease. Vasculitis is a disease which involves the immune system. Here, theimmune system stops offering defense aligned with infection and, consequentlyit fights itself. The precise root of vasculitis is unknown; however, factorstriggering the disease include genetic makeup of an individual, blood cancers,immune system diseases (e.g. rheumatoid arthritis), infections (e.g. hepatitisB), and response to certain drugs. Inflammation of blood vessels may lead toseveral complications. It may block the path of blood flow thereby causingorgans to dysfunction.
According to Vasculitis UK, majorcause of vasculitis may be hereditary or environmental. Moreover, there is alack of approved treatment from the regulatory bodies. According to NationalCenter for Biotechnology Information, in 2011, the therapy rituximab (BiogenIdec/Genentech, Rituxan) happened to be the earliest and only FDA-approvedpossibility for the treatment of vasculitis. This has encouraged thegovernments and the manufacturers alike, for development of new drugs forvasculitis treatment. Moreover, early detection is one of the key factors forthe treatment of the disease. Advent of technology and advanced diagnosis alongwith support from governments and regulatory bodies around the world will fuelthe growth of the global vasculitis treatment market.
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The American Heart Associationsays even though it is not established that inflammation of arteries or veinscauses cardiovascular disease, however, inflammation is widespread for patientswith stroke and heart disease patients and is considered to be an atherogenic(deposition of fat in arteries) response. As the number of cardio vasculardiseases in on the rise, patients with opt for diagnosis and treatment ofvasculitis. Although it is not proven that inflammation causes cardiovasculardisease, inflammation is common for heart disease and stroke patients and isthought to be a sign or atherogenic response; this in turn will propel thegrowth of the global vasculitis treatment market.
Increase in geriatric populationoffers a promising future for vasculitis treatment market
According to Vasculitis UK,usually the frequency of occurrence of vasculitis increases from the 50s;however, but infants and young people can be affected as well. According toAdministration for Community Living, 46.2 million people in the U.S. were abovethe age of 65 in 2014. It is estimated that by 2060 there will be around 98million people falling under this age group. Additionally, latest scientificdevelopments have led to a significant increase in life expectancy around theglobe. As the geriatric population increase, so does the propensity ofoccurrence of vasculitis. As patients have become health aware, and healthcarespend has increased significantly, it can be projected that a part of it willbe spent on the diagnosis and treatment of vasculitis; thereby increasing theglobal vasculitis treatment market.
Manufacturers around the worldare competing on the availability of technologically advanced drugs for thetreatment of vasculitis. Therefore, there is a significant increase in theresearch and development spends incurred by the companies. Government supportis another positive factor that is in favor of the manufacturers. Some of thecompanies operating in the global vasculitis treatment market are RNL BIO Co.,Ltd., GlaxoSmithKline plc, Novartis AG, Troikaa Pharmaceuticals Ltd., HumanGenome Sciences, Inc.¸ Genentech, Inc., F. Hoffmann-La Roche Ltd., AntheraPharmaceuticals‚ Inc., and Teijin Pharma Limited.
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Key Developments
Major players in the market arefocused on approval and launch of novel therapeutics intended for the treatmentof various types of vasculitis. For instance, in July 2019, Pfizer Inc.announced that its RUXIENCE (rituximab-pvvr), a biosimilar to Rituxan(rituximab), intended for the treatment of adult patients with microscopicpolyangiitis, received the U.S. Food and Drug Administration (FDA) approval.
Major institutes and universitiesare focused on R&D activities related to the treatment of vasculitis. Forinstance, in August 2019, researchers from Hospital El Bierzo and BurgosUniversity Hospital, Spain, suggested adoption of disease management based onindividual patient characteristics and levels of disease severity for thetreatment of vasculitis.
Similarly, in August 2019,researchers from Osaka University Graduate School of Medicine, Japan found thatintravenous immunoglobulin was associated with rapid improvements in diseaseactivity and the related biomarkers in patients with active ANCA-associatedvasculitis.
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