U.S. unfractionated heparin is a medication used in the treatment of heart attacks and unstable angina. It is given by injection into a vein or under the skin. It is a fast-acting blood thinner that works together with antithrombin, a natural protein, to block clot formation. Unfractionated heparin as a pharmaceutical is heparin that has not been fractionated to sequester the fraction of molecules with low molecular weight. On the other hand, low-molecular-weight heparin has undergone fractionation for the purpose of making its pharmacodynamics more predictable.
U.S. unfractionated heparin is administered through an intravenous (IV) catheter inserted into a vein or as a subcutaneous injection under the skin. Moreover, it is majorly used in venous thromboembolism (VTE), pulmonary embolism (PE), and deep venous thrombosis (DVT) in patients with increased postoperative complications. Furthermore, because of its reversible anticoagulant effect and its low activity and reversibility, U.S. unfractionated heparin is the preferred treatment for patients at high risk of bleeding complications.
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