Ampicillin market size is forecast to reach US$352.3 million by 2026, after growing at a CAGR of 2.3% during 2021-2026. Penicillin antibiotic drug named ampicillin is used mainly to treat endocarditis, pneumonia, intestines, gonorrhea, respiratory tract, stomach, meningitis, bladder infections, salmonellosis, and other infections. Ampicillin is a sub-category drug under aminopenicillins. Aminopenicillins inhibit the synthesis of the bacterial cell wall and hence successfully kills the bacteria. An increase in the incidence of these infectious diseases among individuals is anticipated to drive the demand for ampicillin drugs among individuals in the forecast period. Since ampicillin is also used to treat secondary bacterial infections caused by COVID-19, the ampicillin market is expected to rise. Increasing investments in the healthcare sector are further anticipated to create opportunities for the growth of the ampicillin industry.
COVID-19 Impact
The health market and the pharmaceutical sector were majorly affected by the pandemic; with a short and long-term time-horizon appearance. However, the coronavirus causes infections leading to pneumonia, multiple organ failure, severe and acute respiratory tract infections, and in severe cases death. Ampicillin is being used for the treatment of the secondary bacterial infection caused due to COVID-19. A significant increase in ampicillin drug production and sales occurred during the COVID-19 epidemic wave has positively affected the growth of the ampicillin market.
Ampicillin Market Report Coverage
The report: “Ampicillin Market – Forecast (2021-2026)”, by IndustryARC, covers an in-depth analysis of the following segments of the ampicillin market.
By Type: Ampicillin Sodium, Ampicillin Sodium for Injection, Ampicillin Sodium and Sulbactam Sodium for injection, Ampicillin Sodium and Cloxacillin Sodium for Injection and Others.
By Indication: Infection (Intestine, Stomach, Bladder, Respiratory Tract and Others), Gonorrhea, Pneumonia, Meningitis, Salmonella Infections, Endocarditis, and Others (Group 3 Streptococcal Infections, etc.) Composite.
By End Users: Adults and Kids
By Intake Method: Oral (Capsules, Tablets, Syrup, Drops, and Others), By Injection into a Muscle and Intravenously
By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies.
By Geography: North America (USA, Canada, and Mexico), Europe (UK, Germany, France, Italy, Netherlands, Spain, Russia, Belgium, and Rest of Europe), Asia-Pacific (China, Japan, India, South Korea, Australia and New Zealand, Indonesia, Taiwan, Malaysia, and Rest of APAC), South America (Brazil, Argentina, Colombia, Chile, and Rest of South America), Rest of the World (Middle East, and Africa)
Key Takeaways
In 2020, the North American region was dominant because of the increasing need for ampicillin with surging gonorrhea cases. According to the Centers for Disease Control and Prevention, in 2019, the overall rate of reported gonorrhea increased by 5.7% in the U.S.
An increase in the incidence of infectious diseases such as pneumonia, gonorrhea, endocarditis, syphilis, salmonellosis, and others, among individuals, is anticipated to drive the demand for ampicillin drugs in the forecast period.
Investments are being made to modernize healthcare infrastructure by the government of developing countries, which is expected to drive the market for ampicillin drugs, globally.
Harmful side effects such as nausea, diarrhea, vomiting, and others, caused by the intake of ampicillin can act as the key hindrance in the growth of the ampicillin drug market over the projected period.
Figure: North America Ampicillin Market Revenue, 2020-2026 (US$ Million)
Ampicillin Market Segment Analysis – By Type
Ampicillin sodium for injection held the largest share in the ampicillin drug market. The dosage of ampicillin sodium for injection is given in different amounts such as in grams, milligrams, milliliters, and is also dependent upon the age and body weight of an individual. Ampicillin sodium for injection is increasingly being used only to treat infections that are strongly suspected to be caused by bacteria, to lessen the production of drug-resistant bacteria. With the rise in such bacterial infections every year ampicillin sodium injection consumption is anticipated to rise, driving the growth of the market.
Ampicillin Market Segment Analysis – By Indication
Pneumonia held the largest share by indication in the ampicillin market in 2020. According to UNICEF (United Nations Children’s Emergency Fund), there are 1400 cases of pneumonia per 100,000 children each year. Also, coronavirus has played a major role in the spread of infections such as pneumonia in the year 2020. According to Health, Pharma & Medtech, in the U.S. as of July 2021, the number of deaths due to pneumonia was 543,773 and that with covid positive pneumonia was 296,282. In addition, according to CDC (Centers for Disease Control and Prevention), death rates due to pneumonia increase with age in adults. Thus, pneumonia played a major role in driving the ampicillin market growth. With the increasing pneumonia cases, it is further anticipated that the market for ampicillin would also rise in the forecast period.
Ampicillin Market Segment Analysis – By End-User
The kid's sector held the largest share in the ampicillin market in 2020 and it is anticipated to grow at a CAGR of 3.1% in the forecast period (2021-2026). Lack of availability of clean water and hygiene and inadequate infection prevention and control triggers the spread of bacteria among individuals. According to United Nations Children’s Emergency Fund, every 39 seconds, pneumonia causes a child's death. Pneumonia is more fatal to children than any other infectious disease, taking the lives of over 800,000 children, including over 153,000 newborns. As per the report on “Pneumonia and Diarrhea Progress Report 2020”, in India, 233,240 deaths occurred due to pneumonia and diarrhea in children under the age of five, and 24,254 deaths took place in China. Also, the group B streptococcal infection and pneumonia found in newborns are treated by ampicillin. Thus, the rising usage of ampicillin to treat bacterial diseases among kids will drive market growth in the forecast period.
Ampicillin Market Segment Analysis – By Intake Method
The oral segment held the largest share in the ampicillin market in 2020. Ampicillin is available in the form of a capsule and a suspension to be taken orally. It is the recommended route of administration in kids due to its non-invasiveness and low risk of pain. Antibiotics taken orally for both adults and kids are less expensive and also available with or without prescription. Intake of ampicillin drug orally even reduces the side effects caused by the intravenous route, such as nausea, vomiting, and diarrhea. Acid hydrolysis does not deactivate aminopenicillins, thus, administration of ampicillin through the oral route is possible. The rapidly rising consumption of ampicillin through the oral intake method will drive the growth of the market.
Ampicillin Market Segment Analysis – By Distribution Channel
Online pharmacies held the largest share in the ampicillin market in 2020. Currently, due to COVID 19 outbreak, the world has gradually shifted towards digitalization. To follow the government-induced norms the need for buying drugs online rapidly increased in the year 2020. Also, to maintain social distancing the preference towards online pharmacies increased among individuals. Thus, the rising consumer’s preference towards online pharmacies in these tough times has raised the growth of the ampicillin market.
Ampicillin Market Segment Analysis – By Geography
North America region dominated the ampicillin market with a share of 38% in 2020 and is projected to dominate the market during the forecast period (2021-2026). The increase in the incidence of sexually transmitted diseases such as syphilis and gonorrhea in the USA, Canada, and Mexico, has raised the demand for ampicillin in this region. In North America, the ampicillin market is supported by the growing organization sizes and increasing application area of ampicillin. According to the Centers for Disease Control and Prevention, in 2019, a total of 616,392 cases of gonorrhea were reported, in the United States. The demand for ampicillin antibiotics is anticipated to rise in the next few years with the increment in incidence and mortality rate of infectious diseases, including pneumonia, STDs, in North America. With favorable government support for raising awareness about infectious diseases among people and a rise in the number of manufacturers of antibiotics in these countries is predicted to boost the market of ampicillin drugs.
Ampicillin Market Drivers
Rising Growth of Infectious Diseases
Ampicillin drugs market is driven globally by increment in infectious diseases such as pneumonia, salmonellosis, endocarditis, syphilis, and gonorrhea as a major factor. Additionally, the incidence of numerous contagious diseases such as urinary tract infections is rising across the globe. According to World Health Organization, globally, every day, more than 1 million sexually transmitted infections (STIs) are acquired. There are predicted 376 million new infections with one of four STIs every year. Also, according to the bulletin of the World Health Organization, reported syphilis cases in Sri Lanka, rose on an average of 5.1 times, by the year 2019. With the rising infectious diseases, the demand for ampicillin is anticipated to drive in the forecast period. Moreover, the global ampicillin drugs market is estimated to rise with the control of bacterial infections and increase in awareness campaigns along with the rise in investments in R&D activities by private and governmental organizations during the forecast period. This will fuel the demand for ampicillin antibiotics in the upcoming years.
Modernization of Healthcare Structure
Investments are being made to modernize the healthcare structure by the government of developing countries in various regions. Globally, with the rising government investments in the healthcare sector, the demand for ampicillin drugs is also estimated to rise. For instance, according to Invest India, the Indian healthcare market is expected to reach US$ 372 Bn by 2022 from US$ 190 Bn in 2020. In China, by 2030 the size of the healthcare industry is expected to reach 16 trillion RMB (US$ 2.3 Million), according to the staff research report on “US-China Economic and Security Review Commission”. Thus, the modernization of the healthcare structure with such investments is anticipated to drive the growth of the market over the forecast period.
Ampicillin Market Challenges
Rising Side Effects of Ampicillin Will Hamper the Market Growth
The effectiveness of a birth control pill can possibly reduced by the use of ampicillin. Side effects of taking ampicillin such as nausea, diarrhea, vomiting, stomach pain, rash, black, or "hairy" tongue, acute inflammatory skin eruption (erythema multiforme), redness and peeling of the skin (exfoliative dermatitis), hive, fever, seizure, inflammation of the small intestine and colon, inflammation in the kidney, noisy breathing, allergic reaction, headache, dark urine, easy bruising or bleeding, persistent sore throat or fever, and many others must be kept into consideration before taking the dosage. Thus, increasing side effects due to the excessive usage of ampicillin is further estimated to hinder the growth of the market.
Ampicillin Market Landscape
Technology launches, acquisitions, and R&D activities are key strategies adopted by players in the ampicillin market. Major players in the ampicillin market are ACS Dobfar S.p.A., Thermo Fisher Scientific Inc., Viatris Inc., Sanofi, Indian Drugs & Pharmaceuticals Ltd., Jagsonpal Pharmaceuticals Limited, Zydus Cadila, Pharmed Medicare P. Ltd., Lyka Hetro Labs, Hetero Healthcare Limited.
