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FabiSpray Nasal Spray lowers covid-19 viral
What is FabiSpray Nasal Spray ?
New Delhi, July 14, 2008 (PTI). A nasal spray was administered to high-risk COVID-19 patients in India. It reduced viral load by 94% in 24 hours and 99% in 48 hours. These results were published in The Lancet Regional Health Southeast Asia journal.
Glenmark, a Mumbai-based pharmaceutical company, conducted the study on Nitric Oxide Nasal Spray in 306 unvaccinated and vaccinated adults suffering from mild COVID-19 at 20 Indian clinical sites.
A seven-day NONS plus standard treatment was evaluated. Fabispray nasal spray was compared to a placebo nasal spray and standard treatment in patients with COVID-19 symptoms. For seven days, NONS was administered by self six times per day as two sprays per nostril.
The Omicron and Delta surges were the perfect conditions for the study. Researchers found that patients at high risk of developing viral infections after receiving NONS showed significant decreases in their viral load within 24 hours. This effect was sustained for seven days.
How is covid-19 spray help ?
The viral load was reduced by 93.7 percent within 24 hours, and 99.9% within 48 hours after treatment with NONS. The authors reported similar results in both vaccinated as well as unvaccinated patients.
Monika Tandon (Senior VP & Head, Clinical Development, Glenmark) said that the robust double-blind trial showed significant efficacy of NONS and remarkable safety. She was also one of the researchers of the study.
Tandon stated in a statement that "this therapy has the potential for making a crucial contribution in COVID-19 management, due to its ease-of-use in the current highly transmissible stage of pandemic."
After receiving manufacturing and marketing approvals from the Drugs Controller General of India, (DCGI), NONS was launched under the brand name FabiSpray.
The statement stated that Nitric Oxide blocks the entry to the nasal passage and kills the virus. It also stops its replication. Fabispray nasal spray is why NONS reduces viral load so quickly.
It stated that the median time to cure viral disease was three days for the NONS group, and seven days for the placebo group.
Researchers concluded that the proportion of immediate contacts who had a positive COVID-19 or became symptomatic remained almost the same in NONS, while it increased numerically in placebo over treatment.