Advances in screening technologies have enabled the identification of interactive gene combinations, enabling the development of lead candidates that leverage the principle of synthetic lethality for cancer treatment
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The USD 8 billion (by 2030) financial opportunity within the synthetic lethality-based drugs and targets market has been analyzed across the following segments:
Type of molecule
Small Molecule
Biologic
Target disease indication
Breast Cancer
Colorectal Cancer
Fallopian Tube Cancer
Gastric Cancer
Head and Neck Cancer
Lung Cancer
Ovarian Cancer
Peritoneal Cancer
Others
Type of synlet target
APE1 / Ref-1
Chk1
GLS1
PARP
Pol θ
PP2A
Wee1
Route of administration
Oral
Intravenous
Key geographical regions
North America
Europe
Asia Pacific
Rest of the World
The https://www.rootsanalysis.com/reports/view_document/synthetic-lethality-based-drugs-and-targets-market-2019-2030-focus-on-dna-repair-including-parp-inhibitors-and-other-novel-cellular-pathways/267.html, report features the following companies, which we identified to be key players in this domain:
AbbVie
AstraZeneca
AtlasMedx
BeiGene
Chordia Therapeutics
Clovis Oncology
GlaxoSmithKline
IDEAYA Biosciences
Mission Therapeutics
Pfizer
Repare Therapeutics
Sierra Oncology
SyntheX Labs
Table of Contents
1. Preface
2. Executive Summary
3. Introduction to DNA Damage and Repair Systems
4. Introduction to Synthetic Lethality
5. Market Overview
6. Company Profiles
7. Emerging Trends on Social Media
8. Publication Analysis
9. Abstract Analysis
10. Academic Grants Analysis
11. Funding and Investment Analysis
12. Target Benchmark Analysis
13. Role of Companion Diagnostics in Synthetic Lethality
14. Market Forecast
15. Concluding Remarks
16. Executive Insights
17. Appendix 1: Tabulated Data
18. Appendix 2: List of Companies and Organizations
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