Creative Bioarray's plasma stability assay can measure the stability of compounds in plasma, helping customers find unstable compound structures and screen prodrugs.
Plasma Stability Assay
Plasma stability plays an essential role in drug discovery and development. In addition to hepatic metabolism, compounds will also be subject to degradation and modification by enzymes in plasma, particularly hydrolases and esterases. Unstable compounds tend to have rapid clearance and short half-life, which leads to poor in vivo performance.
