Dopaminergic therapy in patients with Parkinson's disease has been associated with hallucinations.

Loss of neurons in the brain that use dopamine to communicate is one of the hallmark features of Parkinson’s disease (PD), causing slowness, stiffness, tremor and balance problems.

A combination of levodopa and carbidopa is used to treat Parkinson's disease symptoms and Parkinsonian symptoms that may occur after encephalitis (brain swelling) or neurological damage caused by carbon monoxide or manganese poisoning.