Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.

Hydrocodone 10/325mg, which is available in the market under the brand name Zohydro ER is an opioid medication. It is beneficial in treating prolonged duration severe pain or any moderate pain if other measures are insufficient.