Complex system-wide projects, such as integrated care models, provide substantial challenges for systematic review approaches. Randomized experimental trials, known as the "gold standard," have historically been employed in systematic reviews to look for...

Chronic pain, which includes illnesses like low back pain and osteoarthritis, was recently highlighted as one of the most common causes of disability worldwide by the Global Burden of disease studies in a meta-analysis study.

Chronic pain, which includes illnesses like low back pain and osteoarthritis, was recently highlighted as one of the most common causes of disability worldwide by the Global Burden of disease studies in a meta-analysis study.

Meta-analysis is a technique for summarising the direction and amount of effects found in a collection of empirical investigations looking at the same underlying phenomenon.